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The recent academic paper "Multiplexed Volumetric Bar-Chart Chip for Point-of-Care Diagnostics" [nature.com], developed by researchers at the Department of Nanomedicine, The Methodist Hospital Research Institute in Houston, Texas, presents the research behind the V-Chip (short for Volumetric Bar-Chart Chip).

The chip is about the size of a business card, yet is able to turn about 50 test results into a live, physical bar chart that can be readily read out. This unique feature is achieved by linking a concentration measurement with a proportional production of oxygen, with then causes ink (not blood!) to be displaced along a thin channel in the device.

Put differently, each of the 50 wells is able to contain a unique biomarker test, ranging from insulin and other blood proteins, cholesterol, and even signs of viral or bacterial infection, which all can react to a single drop of blood at the same time. When blood makes contact to these wells, a chain reaction occurs in which an enzyme triggers hydrogen peroxide to release oxygen. The amount of oxygen is indicative of the amount of the biomarker, and pushes the red dye up the bar graph. Accordingly, he chemical reaction being measured becomes the graph.

Watch a short documentary below.

Thnkx Stephie. Via FastCo Design.

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